More open topics

Are dynamic p2p systems that need reliability and don't allow verifying claims doomed? Altruism, redundancy, other factors?
Can we implement reputation with currency? May allow easier decentralization.
Incentives: If anonymity for all requires each user doing similar things, how do we deal with users who don't want as much anonymity?
Do we have to abandon statistical rigor in the face of dynamic systems and adversaries?